Biomedical research in MCDB spans a wide variety of areas and medical fields from basic research all the way to pre-clinical experimentation and direct medical application. MCDB researchers investigate molecular disease mechanisms, diagnostic approaches and biomarkers, pharmacological interventions and novel drug design, therapies including stem-cell therapy. Diseases that are being investigated in MCDB labs include various forms of cancer, Alzheimer's disease, macular degeneration, viral and bacterial infectious diseases, kidney diseases, addiction, immunological diseases, diabetes. Investigators in MCDB use state-of-the-art methods in biochemistry and biophysics, cell and molecular biology, genetics and genomics, nanotechnology, microfluidic, and microarray platforms, animal models from worms and flies to rodents. In addition, numerous and extensive collaborations exist with clinical institutions, pharmaceutical and biotech companies, and research laboratories in disciplines such as physics, material science, engineering, nanotechnology, and marine science.